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Neuropeptide Y Receptor 2 Phosphorylation Assays

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OD signals in pS351/pS354-NPY2 Phosphorylation Assay
pS351/pS354-NPY2 Phosphorylation Assay Kit
The pS351/pS354-NPY2 Phosphorylation Assay Kit allows determination of NPY2 Phosphorylation in 96-well plates without the need for Western blot analysis.
420.00 € * 600.00 € *
Details
30
NEW
OD signals in pS354/pT356-NPY2 Phosphorylation Assay
pS354/pT356-NPY2 Phosphorylation Assay Kit
The pS354/pT356-NPY2 Phosphorylation Assay Kit allows determination of NPY2 Phosphorylation in 96-well plates without the need for Western blot analysis.
420.00 € * 600.00 € *
Details
30
NEW
OD signals in pS359/pS364-NPY2 Phosphorylation Assay
pS369/pS374-NPY2 Phosphorylation Assay Kit
The pS359/pS364-NPY2 Phosphorylation Assay Kit allows determination of NPY2 Phosphorylation in 96-well plates without the need for Western blot analysis.
420.00 € * 600.00 € *
Details

NPY2

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective NPY2 receptor antagonist. NPY2 receptor desensitization and internalization are regulated by phosphorylation of carboxyl-terminal serine351/serine354 (pS351/pS354-NPY2), serine354/threonine356 (pS354/pT356-NPY2) and serine351/serine354 (pS369/pS374-NPY2). This nomenclature refers to the human NPY2 receptor. This phosphorylation motif is highly conserved across species and very similar in mice and humans. For more information on NPY2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Beck-Sickinger, A., Colmers, W. F., Cox, H. M., Doods, H. N., Herzog, H., Larhammar, D., Michel, M. C., Quirion, R., Schwartz, T. and Westfall, T. (2019) “Neuropeptide Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F46/2019.4.

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective... read more »
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Neuropeptide Y Receptor 2 Phosphorylation Assays

NPY2

The NPY2 receptor can be found in CNS, intestine and heart. Signal transduction by the NPY2 receptor includes PTX-sensitive inhibition of cAMP production. BIIE0246 is a selective NPY2 receptor antagonist. NPY2 receptor desensitization and internalization are regulated by phosphorylation of carboxyl-terminal serine351/serine354 (pS351/pS354-NPY2), serine354/threonine356 (pS354/pT356-NPY2) and serine351/serine354 (pS369/pS374-NPY2). This nomenclature refers to the human NPY2 receptor. This phosphorylation motif is highly conserved across species and very similar in mice and humans. For more information on NPY2 pharmacology please refer to the IUPHAR database. For further reading refer to:

Beck-Sickinger, A., Colmers, W. F., Cox, H. M., Doods, H. N., Herzog, H., Larhammar, D., Michel, M. C., Quirion, R., Schwartz, T. and Westfall, T. (2019) “Neuropeptide Y receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database”, IUPHAR/BPS Guide to Pharmacology CITE, 2019(4). doi: 10.2218/gtopdb/F46/2019.4.

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